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Sarcopenia | The critical role of musculoskeletal health in longevity

Movement is essential for maintaining health and independence throughout life.1 Regular physical activity supports muscle strength, joint stability, and metabolic function, helping to prevent frailty and chronic disease as we age1 and providing the independence required to support social connection. However, a significant contributor to the gap between lifespan (total years lived) and healthspan (years lived in good health), is sarcopenia,2 a major global public health concern affecting 20% of people over the age of 70, and 50% of people over the age of 80.3 Alarmingly, up to 19% of the global population over the age of 60 currently suffer from sarcopenia,4 making it a critical concern for healthy ageing.

Characterised by a progressive loss of skeletal muscle strength, mass, and quality, sarcopenia leads to a myriad of adverse health outcomes, such as mobility disorders, increased fall risk and fractures, disabilities, and an increased risk of other musculoskeletal disorders, including osteoporosis.5 This debilitating condition also impacts the ability to perform activities of daily living, resulting in loss of independence and a decline in overall quality of life.5

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