Magnesium is a cofactor for over 300 enzyme systems. It is a macromineral widely distributed in the plant and animal foods.

Omega-3 fatty acids are chondroprotective and reduce inflammation. This can result in improvements in pain and function in patients with arthritis.

The B complex vitamins are thiamine (B1), ribo avin (B2), niacin (B3), pantothenic acid (B5), pyridoxine (B6), folate (B9), cyanocobalamin (B12) and biotin.

As vitamin C is not extensively stored in the body, daily dietary consumption is required.