Restless legs syndrome (RLS), also called Willis-Ekbom Disease, is a common neurological disorder characterised by an irresistible urge to move the legs.1 It is often associated with unpleasant sensations, such as cramping, soreness, or a ‘creeping, crawling’ feeling which is typically felt in the calf, however, can be experienced anywhere along the leg.2 These symptoms can vary in duration and severity for the individual, and most commonly occur at rest or in the evening, therefore impacting sleep.3 As the fourth leading cause of insomnia,4 RLS is a public health concern, with insufficient sleep linked to the development of numerous health conditions, including chronic respiratory diseases, dementia, mental health disorders, musculoskeletal issues, and cardiometabolic diseases.5 It is estimated to affect 7% of the global population,6 with women twice as likely to suffer from the condition than men.7
Due to the debilitating nature of this condition as a result of pain and sleep disruption, RLS can significantly reduce quality of life.4 Until recent years, dopaminergic agents have been widely considered as the first-line pharmacological treatment for RLS, however, long-term treatment can lead to a progressive worsening of RLS symptoms.8 Therefore, addressing any underlying cause and finding natural alternatives to support this condition is crucial.
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